Lighting the Way for Children With Brain Tumors

Recalling the treatments her daughter has had over the past year for an aggressive, very rare type of brain tumor known as atypical teratoid rhabdoid tumor, or ATRT, Audrey Taylor says it’s like watching a game where your favorite sports team keeps losing and then regaining the lead. “There are so many times when you […]

Read More →

Study Could Help Predict Aneurysm Risk for Kids with Kawasaki Disease

In honor of National Kawasaki Disease Awareness Day on January 26, we are sharing the story of Olivia, a 9-year-old who lives with the disease. Research at Seattle Children’s aims to improve life for children with this condition who are at risk for aneurysms. When Olivia Nelson was 3 years old, her parents noticed that […]

Read More →

Secret to Sepsis May Lie in Rare Cell

In a paper published in Nature Immunology, scientists from Seattle Children’s Research Institute reveal how a rare group of white blood cells called basophils play an important role in the immune response to a bacterial infection, preventing the development of sepsis. Researchers say their findings could lead to better ways to prevent the dangerous immune […]

Read More →

New Findings on Concussion in Football’s Youngest Players

New research from Seattle Children’s Research Institute and UW Medicine’s Sports Health and Safety Institute found concussion rates among football players ages 5-14 were higher than previously reported, with five out of every 100 youth, or 5%, sustaining a football-related concussion each season. Published in The Journal of Pediatrics, the study summarizes the research team’s […]

Read More →

Researchers Share Key Learnings From T-Cell Immunotherapy Trials

Seattle Children’s doctors and researchers continue to believe chimeric antigen receptor (CAR) T-cell immunotherapy has the power to revolutionize pediatric cancer care. Over the past year, they have made tremendous progress with the promising therapy, which has given patients like Harper Beare, Erin Cross and Milton Wright a second chance at life. Seattle Children’s recently […]

Read More →

Tailor-Made Fish Help Explain Genetic Conditions in Children

More than five years ago, when Dr. Lisa Maves, a scientist at Seattle Children’s Research Institute, first started using CRISPR to make genetic alterations in zebrafish, she saw the potential for the minnow-sized fish to help doctors understand how genetic mutations contribute to a child’s condition. “Essentially, we set out to make a patient’s fish,” […]

Read More →

Two Years Cancer-Free, Erin Advocates for T-Cell Immunotherapy

Each morning, 8-year-old Erin Cross springs out of bed excited to go to school. A third grader in Chester, England, she loves science and math, and imagines a future as a researcher making “potions” in a lab. She loves cracking jokes, rugby and playing make-believe games with her friends on the playground. For Erin, who […]

Read More →

Seattle Children’s Brings Cancer Immunotherapy to a Global Stage

T-cell immunotherapy continues to take center stage as one of the most promising new cancer therapies of our time. What once sounded like a dream – reprogramming a person’s own immune system to fight cancer – is remarkably becoming a reality. What’s more; doctors and researchers in our own backyard are leading the way in […]

Read More →

Milton Wright Finds His Way Back ‘Home’

Milton Wright III has only worked at Seattle Children’s for a couple months, but the hospital has been his second home for much of his life. Milton’s childhood unfolded within Seattle Children’s walls — making friends, experiencing loss and facing death more times than he can count. Today, Milton is back at Seattle Children’s — […]

Read More →