A Stroke of Genius

Strokes come in many shapes and sizes. In children and adults, strokes often present sudden limb or facial numbness, confusion and dizziness. But some strokes that cause clots to develop in the small blood vessels of the brain don’t exhibit any symptoms at all. Studies have shown that hundreds to thousands of these small, asymptomatic […]

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Madeline Pursues New Dream After Overcoming Cancer Four Times

When Madeline Boese was 14, she had visions of pointe shoes, tutus and sugar plums dancing in her head. She dreamed of becoming a professional ballerina, and hoped for a future in the spotlight doing what she loved. Unfortunately, her body had different plans. One day in ballet class in December 2006, she noticed an […]

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Researchers Ready B Cells for Novel Cell Therapy

Scientists at Seattle Children’s Research Institute are paving the way to use gene-edited B cells – a type of white blood cell in the immune system – to treat a wide range of potential diseases that affect children, including hemophilia and other protein deficiency disorders, autoimmune diseases, and infectious diseases. If successful, their research would […]

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Scientist Brings First-Hand Perspective to Fight Against Malaria

Growing up in Ghana, a sub-Saharan country on the west coast of Africa, Dr. Nana Minkah, a scientist at the Kappe Lab, endured the unenviable “rite of passage” contracting malaria multiple times as a child. While he doesn’t remember the early years when the associated high fever caused hallucinations, he has distinct memories of later […]

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Scientists Find Clues to Rare Mutation Hours After Toddler’s Brain Surgery

At 5 months old, Tyler Cassinelli, now 3, was battling both liver cancer and intractable epilepsy. When he was at Seattle Children’s preparing to undergo cancer treatment, Tyler had a seizure that stopped his breathing. “It was one of the scariest moments of my life,” said Jane Cassinelli, Tyler’s mother. “We could see his stats […]

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Doctor Creates Virtual Reality Simulation to Save Babies’ Lives

Wanting to do something different to address the alarmingly high number of newborn deaths in low income countries, Dr. Rachel Umoren, a neonatologist at Seattle Children’s, turned to virtual reality (VR). As mobile phone-based VR programs became increasingly accessible, Umoren thought the emerging technology could offer a better way to equip health care providers with […]

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Smoking During Pregnancy Doubles the Risk of Sudden Unexpected Infant Death, Study Warns

The first findings to result from a collaboration between Seattle Children’s Research Institute and Microsoft data scientists provides expecting mothers new information about how smoking before and during pregnancy contributes to the risk of an infant dying suddenly and unexpectedly before their first birthday. According to the study published in Pediatrics, any amount of smoking […]

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New Drug Trial Gives Hope for Treatment-Resistant Epilepsy

For the first time in his life, Shanahan “Shanny” Dameral, 19, has a girlfriend. Soon, he’ll be graduating with a high school diploma and looking for his first job on the Kitsap Peninsula. What seems routine for many is a big deal for Shanahan and other children living with treatment-resistant or intractable epilepsy. For reasons […]

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