New Discovery Paves Way for Next-Generation Malaria Vaccine

In an unprecedented first, scientists at Seattle Children’s Research Institute have developed a genetically attenuated parasite (GAP) that arrests late in the liver stage of human malaria. Their findings published in JCI Insight pave the way for a novel, next-generation GAP vaccine against Plasmodium falciparum, the parasite that causes the deadliest form of malaria in […]

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Engineered T Cells for Type 1 Diabetes Move Closer to Clinic

For much of the last decade, Dr. David Rawlings, director of Seattle Children’s Research Institute’s Center for Immunity and Immunotherapies, has dreamed of developing a therapy for children with type 1 diabetes that doesn’t involve insulin injections but uses a person’s own immune cells to target and treat the disease. Now, new research and a […]

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June 1, 2020: Seattle Children’s Statement on Acts of Racism Across the U.S.

We are writing to acknowledge the tragic acts of violence and racism happening across our country. The senseless killings of Ahmaud Arbery in Georgia, Breonna Taylor in Kentucky, and George Floyd in Minnesota leave us sickened and heartbroken. While we share our grief with these families and their communities, we must also acknowledge with sorrow […]

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Get Care When Your Child Needs It

My two-year-old son Malachi is a medically-complex Seattle Children’s kiddo and a “frequent flyer” here at the hospital. We visit the hospital often—for clinic appointments, routine procedures, sicknesses and medical emergencies. Malachi was diagnosed with Spina Bifida before he was born. He had several lifesaving operations in his first few months with us including spine […]

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Are Children Making Antibodies That Will Protect Against Future COVID-19 Infections?

More than 50 research studies to understand, detect, treat and prevent the novel coronavirus in children and families have launched at Seattle Children’s since the virus emerged in late 2019. The following post is part of the “Quest(ion) for Discovery” series highlighting this research in progress and the search for answers that could result in […]

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New Program Helps Families with Mental Health Crises

In recognition of Mental Health Month, On the Pulse will be sharing valuable resources and inspiring patient stories each week to guide individuals and families struggling with mental health issues and help destigmatize the topic of mental health in our society. One late afternoon in April, Jessie Early noticed something was wrong her with 7-year-old […]

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