Eric Turner, MD, PhD, of the Center for Integrative Brain Research at Seattle Children’s Research Institute has his sister and her pet rat to thank for his most recently-published study which identified a new kind of gene mutation which causes ear malformations in rats and mice. Findings from the study are expected to help researchers identify the gene mutations which cause these types of malformations in humans.
More developmental monitoring of children with skull deformation needed, researchers say
As many as 30 percent of all infants may have deformational plagiocephaly, also known as positional plagiocephaly, which is characterized by asymmetry and flattening of the head caused by external pressures. In previous studies, infants and toddlers with this condition have been shown to experience delays in development compared to unaffected children.
Researchers at Seattle Children’s Research Institute wanted to find out if these developmental delays persisted as children grew older. The researchers studied the development of 224 children with deformational plagiocephaly from infancy ( months, on average) through 36 months of age, comparing them to 231 unaffected children. This is the first scientifically rigorous study to examine development in preschool-age children with deformational plagiocephaly compared to a control group of kids without the condition.
Results of the study were published today in the journal Pediatrics. The findings indicate that children with deformational plagiocephaly continued to score lower on development measures than unaffected children at age 36 months. Differences between children with and without deformational plagiocephaly were largest on measures of language and cognition, and smallest on measures of motor skills such as balance, jumping and running. Read full post »
In October 2010, Heather Landis received a phone call no expectant mother ever wants to receive. At five months pregnant with their second child, the doctor told Heather and her husband Dale that the baby girl they were expecting would be born with a cleft lip and palate, birth defects that occur early in pregnancy. After the initial shock of the diagnosis, the Landis’s began preparing themselves for the difficult road that awaited them. Struggling with her emotions, Heather put what she was feeling into a candid and personal blog detailing the months before and after the birth of her daughter, Danielle.
Her blog detailed Danielle’s trips to Seattle Children’s Hospital, where Dr. Hitesh Kapadia initiated the repair process using a nasoalveolar molding (NAM) device – a non-surgical method of reshaping the gums, lips, and nostrils of children with large cleft lips and palates prior to surgery. Following months with the NAM, the craniofacial team lead by Dr. Raymond Tse performed multiple surgeries to correct Danielle’s cleft lip and palate. Danielle is currently doing very well and her cleft lip and palate were successfully repaired by Danielle’s care team. The team’s courageous efforts, collaborative spirit, and amazing success also inspired Dale to apply for a job at Seattle Children’s, where he works today.
The Landis’ story is told in a compelling photo slideshow narrated by Heather, using entries from her months of blog posts and photos taken by the family during their difficult – but ultimately successful – journey.
If you’d like to arrange an interview with Heather or Dale Landis, or a member of Danielle’s care team, please contact Children’s PR team at 206-987-4500 or at email@example.com.