Making Sense of Restless Sleep Disorder in Children

An international panel of sleep experts is adding a new pediatric sleep disorder they call restless sleep disorder, or RSD, to parents’ and pediatricians’ radars. Led by Seattle Children’s pediatric sleep specialist, Dr. Lourdes DelRosso, the group shares their consensus on a medical definition of RSD in a new paper published in Sleep Medicine. Known […]

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Six Years Later: Immunotherapy’s Tiniest Trial Participant Is Living With “So Much Joy”

In the fall of 2013, Maggie and Andy Oberhofer watched their tiny, 8-month old daughter, Greta, fight for her life in the Pediatric Intensive Care Unit (PICU) at Doernbecher Children’s Hospital in Portland, Oregon. Greta had just been through a bone marrow transplant to treat her highly aggressive leukemia. Shortly after, she took a turn […]

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Reaching New Heights: Champion for Pediatric Research Reflects on National Role

As a newly appointed member of the U.S. Department of Health and Human Services Secretary’s Advisory Committee for Human Research Protections (SACHRP), Dr. Douglas Diekema has always had a passion for interpreting and applying the regulatory laws for research involving human subjects to support the children and families that participate in research at Seattle Children’s. […]

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With Cancer on the Back Burner, Champion Junior Chef Cooks Up His Dreams

After winning the Food Network’s Chopped Jr. reality TV cooking competition, Fuller Goldsmith, 16, was well on his way to achieving his dreams of becoming a professional chef. It was a future that was soon in jeopardy when life for the aspiring chef took an uncertain, but all too familiar turn. In late 2018, Fuller […]

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New Discovery Paves Way for Next-Generation Malaria Vaccine

In an unprecedented first, scientists at Seattle Children’s Research Institute have developed a genetically attenuated parasite (GAP) that arrests late in the liver stage of human malaria. Their findings published in JCI Insight pave the way for a novel, next-generation GAP vaccine against Plasmodium falciparum, the parasite that causes the deadliest form of malaria in […]

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Engineered T Cells for Type 1 Diabetes Move Closer to Clinic

For much of the last decade, Dr. David Rawlings, director of Seattle Children’s Research Institute’s Center for Immunity and Immunotherapies, has dreamed of developing a therapy for children with type 1 diabetes that doesn’t involve insulin injections but uses a person’s own immune cells to target and treat the disease. Now, new research and a […]

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Are Children Making Antibodies That Will Protect Against Future COVID-19 Infections?

More than 50 research studies to understand, detect, treat and prevent the novel coronavirus in children and families have launched at Seattle Children’s since the virus emerged in late 2019. The following post is part of the “Quest(ion) for Discovery” series highlighting this research in progress and the search for answers that could result in […]

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Should Schools Go Screen-Free: Study Reveals Significant Portion of U.S. Middle and High Schools Do Not Limit Phone Use During Lunch or Recess

The latest screen-time related research from Dr. Pooja Tandon, a child health and development expert at Seattle Children’s Research Institute, was inspired by her oldest son. “When my son entered middle school, I learned that students in many middle and high schools were allowed to have their phones with them at all times,” Tandon said. […]

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