Matched to the Perfect Target, Drug Dramatically Shrinks Tumors in All Ages, Multiple Cancers

EDITOR’S UPDATE: The U.S. Food and Drug Administration approved the cancer drug Vitrakvi (previously known as larotrectinib). Vitrakvi is indicated for the treatment of adult and pediatric patients with metastatic or unresectable solid tumors that have a NTRK gene fusion without a known acquired resistance mutation, and have no satisfactory alternative treatments options or whose cancer has […]

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3D-Printed Heart Transforms Family’s Understanding of Complex Heart Disease

Rachael Satake holds a 3D-printed replica of her son’s heart condition in her hands during a recent appointment at Seattle Children’s Heart Center. For the first time since learning about the defect midway through pregnancy, she clearly sees how the surgeries he has undergone are helping his heart work despite having only one ventricle. Her […]

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Montana Twins’ Hearts Beat in Harmony Following Unexpected Surgery Days After Birth

Leigh Sturges recalls the day she and her husband, Zach Sturges, learned they were having twins. Seven weeks into their first pregnancy, the Bozeman, Montana, family entered a state of happy shock. “We couldn’t believe it when heard two heart beats on the ultrasound,” she said. “We were realistic about the challenges ahead, deciding it […]

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Study Finds Neuron Inhibition May be Key in New Treatments for Addiction

A new study published by researchers from Seattle Children’s Research Institute reveals how neurons in the brain fuel drug-seeking behavior following compulsive drug use. Their findings, published online in Addiction Biology, suggest inhibiting one group of neurons’ activity may prove to be a highly effective treatment for reducing relapse in recovering addicts. While the science […]

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Surgery Frees Lillee from Seizures Medication Couldn’t Stop

When 4-year-old Lillee Haynes runs through the doors of Seattle Children’s South Clinic for her speech therapy appointment and heads straight for a table covered in crayons, it’s hard to imagine that nearly two years ago she faced hundreds of epileptic seizures each day. “Her seizures happened so often that I installed a camera above […]

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